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Serological Cross Reaction among Sonle Causative Agents of WomenAbortions (Toxoplasma gondii & Cytomegalo Virus & Rubella Virus),rvith the Incidence of Hepatitis Virus (B &C) | ||
| Tikret Journal of Pharmaceutical Sciences | ||
| Article 1, Volume 3, Issue 2, 2007, Pages 102-111 | ||
| Author | ||
| Yahya Gargies Salman | ||
| Abstract | ||
| Primary maternal infection r,vith infectious agents of abortions in rvomen is frequentlyassociated with transplacental transmission to the fetus. This study lvas conducted to test the utilityELISA assay to detect recent infection with Toxoplasma (TOXO), Rubella virus (RV),Cytomegalovirus (CMV), the incidence of viral hepatitis B (HBS) & C (HCV) in addition thedetermination of cross reactivity among serological tests. Three hr-rndred forty three rvomen withhiglr risk of pregnancy (1vtro had previous recurrent abortion & congenital abnormalities) & 60normal pregnancies (control) rvere tested for the preserlce of the tests that described in above. Theall rate of int'cctious agents was 22.15 % that divided into 8.88%,8.02oA & 4.84 Yrfor RV, CMV,& Toxo antibodies respectively. Igm Ab of RV(3 1 .5%) 'uvas higher than CMV ( 11 .6%) &. Toxo(339% ) P<0.05.While IgG Ab shorvs the reveres as l7o/o for'l'oxo, follorved by 6.75% 8d7.89%for RV& CMV respectively P<0.05.Relationship betr.r'cen distribution ol'Toxo Ab concerning agelvas not significant P>0.05. inciclence of FICV shou's eqrrality rates 2.63% rvithin sero-positiveToxo,RV&CMV, r,vhile HBS shorvs high occllrrence in sero-positive for RV ( 5.26%) than in seropositivefor foxo & CMV(1.31% )P<0.05. Relationship betw'een fi'equency of abortions &stillbirths& infectious agents',vas significant P<0.05. In addition.relationship betri'een womenoccupations & frequency of scro-positive reveals significance P<0.05 especially, in sera ofhomemakers (houselvives) than other womcrl occupations. Control groups rvcre negative for viralhepatitis &Toxo, except few cases>0.05.Iicy rvords: Abortions, Stillbirth, Totoplasma, Cytouregalovirus, Rubella, HepatitisVinrses B & C. | ||
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