Evaluation of Serum Alanine aminotransferase, Aspartateaminotransferase and Alkaline phosphatase in Adult ObeseNinava People.

H. Al-Hamdani, A; Isra,

	Evaluation of Serum Alanine aminotransferase, Aspartateaminotransferase and Alkaline phosphatase in Adult ObeseNinava People.
Tikret Journal of Pharmaceutical Sciences
Article 1, Volume 6, Issue 1, 2010, Pages 63-69
Authors
a H. Al-Hamdani;
Abstract
Obesity is a well known cause of a lot of health problems, these problems can befurther evaiuated by biochernical studies. In the present study 3 biochemicalparameters represented as: Alanine aminotransferase (ALT), Aspaftateaminotransfetur. leSf; and Alkaline phosphatase (ALP) has been measured in bloodof 69 apparentiy healthy obese subjects (30 males& 39 females) which divided intotwo subgroups according to body mass index (BMI) (30- 34.9) & (35- 39.9). Thecontrol groui in"tuded 32 apparently healthy with normal weight subjects. The aimof this research is to study the effect of obesity on the activity of aminotransferaseenzymes (ALT& AST), and alkaline phosphatase (ALP) in Ninava compared to.o,1irol group (sr-rbjects with normal weight), in addition, to study the biochemicalchanges of these enzymes within obese group which classified according to the BMIand sex. According to the results which recorded in this study, there was a significantincrease in the activity of ALT, AST, and ALP in obese subjects when compared tocontrols, also there is no significant effect of BMI on these enzymes in obese grouprvith a higher mean activities of three enzymes in class II obese group (BMI 35- 39 '9).The results also showed no significant difference between male and female in obesesubjects for the mean activities of these enzymes.

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