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The therapeutic effect of Nigella setiva seed oilin treatment of chronic urticaria | ||
| Tikret Journal of Pharmaceutical Sciences | ||
| Article 1, Volume 1, Issue 1, 2005, Pages 1-6 | ||
| Authors | ||
| ahmed M. Al; Abdul Ghani M. Al-Samarai; Ali E. Al-Snafi | ||
| Abstract | ||
| Urticaria is a common disease which affects an approximately 15-25o/o of thepopulation at some point during their life time.Chronic urticaria indicates the presence ofhives for a protracted period (>6weeks).Antihistamines, steroids and immune suppressants are needed for the treatment ofchronic urlicaric.This study was designed to investigate the therapeutic effects ofNigella sative oil in the heatment of chronic urlicaria. The results showed that 400mg twice daily of Nigella sativa oil (in gelatin capsule) was significantly increasecure rate. It also significantly decreases logle IgE and improves tolerability ofpatientsto exacerbating factors.The effects of Nigella sativa oil in urticaria could be attributed to inhibition ofhistamine release, blocking of histamine effects and inhibition of ecosanoidesformation lrom arachidonic acid | ||
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