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Topical Nitroglycerin versus Lateral fnternal Sphincterotomyin Treatment of Chronic Anal Fissure | ||
| Tikret Journal of Pharmaceutical Sciences | ||
| Article 1, Volume 4, Issue 1, 2008, Pages 69-73 | ||
| Author | ||
| Makki Allaw | ||
| Abstract | ||
| Background: Anal fissure is common conditions that can affect people of all ages. Most anal fissures areat the rear of anal opening in line with cleft of the buttocks. There are many meihods of treatment suchas: medication by topical nitroglycerin or nifedipine paste or butulinum toxin injection or surgery bylateral internal Sphincterotomy or V-Y advancement flap.Obiectives: Is to compare the result of topical GTN (chemical Sphincterotomy) as primary treatment ofchronic anal fissure with lateral internal Sphincterotomy.Methods:Setting: In outpatient clinic and Tikrit teaching hospital from Jan. 2006 to Octo.2007.Design : prospective study.This study compares the results of two different methods of treatment (chemical sphinecterotomy&lateralinternal Sphincterotomy) in 84 cases of chronic anal fissure regarding the efficacyand complicaiion ofthcse procedurcs.These cases were randomized in equal number into trvo groups:Group l: rvcre treated by chcmical Sphincterotomy.Croup 2: rverc treated by lateral internal Sphincterotomy.The avcragc pcriod of follorv up aftcr complction of treatmcnt was 3 months for both groups.Rcsults:Synrptornatic improvcntcnt occurs in 30 paticnts trcatcd by clrcrnical Sphinctcrotomy (71,42%) at lZrvccks follorving trcatntcnt and 39 paticnts (92.85%) trcatcd by latcral intcrnal Splrinctcrotomy.No irtrprovctt'tcttt occttrs itt 3 cascs (7.15%) trcatcd by chcntical Sphilctcrotonly and no casc rvSo rvastrcatccl by latcrnl intcrnal Sphinctcrotonry.Cottclttsiott: [:rottt tltis sttrdy rvc f rncl thlt chcrnical Splrinctcrotonry inducc rapid healing of clrrorric analflssttrc rvith 71.42% ratc itt cotttparisort to lntcral intcrnal Sphinctcrotonry rvitlr a92.85o/o lrcaling ratcallcr l2 rvccks trcatnrcnt. | ||
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