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Chemotherapy and other treatment modalitities in children with Neuroblastoma | ||
| Tikret Journal of Pharmaceutical Sciences | ||
| Article 1, Volume 4, Issue 1, 2008, Pages 44-56 | ||
| Authors | ||
| Ahmed H. AL-ANEE; Salma Al- Haddad | ||
| Abstract | ||
| Neuroblastoma is the second most common solid tumor in the study reviewed first decade of life. A retrospective (39) children treated for N.B. at Al-Mansour Teaching n"rprrrir"r children from Jan. lst 2001 to Dec' 3lst 2006, the clinical data were analyzed. Thirty ninJpaiiJnir'*.r. included (23) males (59%) and (16) females (41%), the median-age at diagnosis was (4g) months .The abdomen was the site of initiaf tumor in3l(79.4%) of patients, hypertensiIn is found in 6 out of eleven cases (54.5%) and hepatomegaly is found in 53.8% of cases. Anemia was recorded in 26(6g.4%) ofpatients.Stage IV was the predominant clinico-pathologicat stage .The median survivar *u. i3.s *oni1,, (range I month - 45 months)' There was significant association between the stage of the disease and event free survival. There was no statistically significant association between the agi at diagnosis and the outcome because abour l5 cases (38%) of the patients lvere lost to follow-r,p .rnJrti,ay recommends the use of the new method for early diagnosis and treatment of the disease like ihe ur. of ui'tologo,,, uon. *orrorv transplant and the usc of antibodies directed against the tumor cells. | ||
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