Abstract:
This study was carried out to determine the effect of the daily injection of oxytocine and promocriptein for 21 days on some hematological and biochemical parameters in mature domestic male rabbits.
Thirty mature male rabbits were randomely divided into the five equal groups. The 1st group was injected by oxytocine only (0.1 mL, i.m ), the 2nd group was injected by oxytocine (0.1 mL, i.m) and bromocriptein (0.5 mg, i.m), the 3rd group was injected by oxytocine (0.2 mL, i.m) and bromocritein (0.5 mg, i.m) , the 4th group was injected by bromocritein only (0.5 mg, i.m) , and the 5th group was injected by normal saline as a control group.
Blood sample were obtained weekly (7,14,21 days) after injection for hematological and biochemical measurements.
The results showed :- a significant decrease of RBC number in the 3rd group and a significant increase in the 1st group. Hb values was highly significant in the 1st group, PCV values showed no significant differences between treated groups. WBC count revealed a significant increase in the 4th group, and a significant decrease in the 1st group.
The treated substances of the present study showed no effect on total protein, while albumin concentration was significantly decrease in the treated groups.
ALP values showed significant differences among groups. It's value showed a highest level in the 4th group and lowest level in the 5th group. GPT values also differed among groups, its level was increased in the 5th group and decrease in the 1st , 2nd, and 4th groups. GOT results recorded a significant increase in the 4th group, while 1st and 2nd groups recorded a significant decrease.
The results revealed a significant effects of the period (7,14, 21 days) on RBC count , total protein, albumin and GOT especially at 21 day after injection. |