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Frequency of HLA Antigens in a Sample of Iraqi Brucellosis Patients | ||
| Baghdad Science Journal | ||
| Article 1, Volume 9, Issue 1, 2012, Pages 86-92 | ||
| Authors | ||
| Ammna N. Jasim; Aaiad H. A. Al-Rikaby; ; Ali H. Ad | ||
| Abstract | ||
| Fifty one patients with serologically confirmed brucellosis and 70 healthy controls were phenotyped for HLA-A, -B, -DR and -DQ antigens by using standard microlympho-cytotoxicity method, and lymphocytes defined by their CD markers (CD3, CD4, CD8 and CD19). The results revealed a significant (Pc = 0.001) increased frequency of HLA-DR8 (41.18 vs. 10.0%) in the patients . A significant increased percentage of CD8+ lymphocytes was also increased in the patients (25.15 vs. 22.0%; P = 0.006), while CD3+ lymphocytes were significantly decreased (75.1 vs. 79.4%; P = 0.02). | ||
| Keywords | ||
| Brucellosis; HLA; CD markers | ||
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