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The effect of candida albicans on some blood and biochemical parameters in laboratory mice . | ||
| The Iraqi Journal of Veterinary Medicine (IJVM) | ||
| Article 1, Volume 29, Issue 1, 2005, Pages 43-50 PDF (0 K) | ||
| Authors | ||
| Hnan A. muhammed; Ekbal A. Hazam; muhammed hasan khuder | ||
| Abstract | ||
| In the present study , 32 white mice Balb /C (two months age ) were used ,there were divided into four equal groups . Three groups were injected with fungal suspention of candida albicans in doses of 1x106 ,1x108 and 3x108 cell/ml ,whereas the fourth group was regarded as control and injected with 0.5 ml normal saline solution . All were dissected after 6 days of injection to study the physiological effect of the yeast on blood , which include RBCand WBC count , Hb concentration and PCV ratio . And on biochemical content which include the determination of protein , glycogen and cholestrol in liver ,kidney and muscles . The results showed that the number of RBC were decreased ,while WBC were increased in the injected mice ,but there were no signifficant effect on PCV and Hb . On the other hand ,cholestrol values were decreased significantly in the injected mice in comparison with control,but this decrease was varied in different tissues (P>0.01).The value was lower in liver ,whereas no signifficant difference was found between Kidney and muscles . Protein values were not signifficantly different in comparison with control , but it was different among tissue studied .muscles was the highest value and the liver was lowest . Glycogen decreased signifficantly in comparison with control ,but not among tissues. | ||
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