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OPTIMUM CULTURAL CONDITIONS FOR THE PRODUCTION OF ANTIMALARIAL AGENT BY STREPTOMYCES ISOLATES | ||
| Iraqi Journal of Biotechnology | ||
| Article 1, Volume 4, Issue 1, 2005, Pages 126-143 | ||
| Abstract | ||
| ABSTRACT Twenty Six local isolates of Streptomyces spp. were screened for their antimalarial activity . Four isolates showed activity against P.vivax , Streptomyces sp.1 have the highest activity against all parasite (P.vivax) stages during 48 hours in compareson with other isolates, the inhibition percentage was 88.38%. Optimum cultural conditions for production of antimalarial agent by Streptomyces sp1 were studied. The maximum production of antimalarial agent was obtained by using modified (S) medium, which consist of 1.0% starch (carbon source), 1.0% broad bean powder (nitrogen source), 1.0% NaCl , pH 7.5, inoculum volume 3%, and incubated at 30 ° C with shaking (150 rpm) for 5 days. _________________________________________________________________ | ||
| Keywords | ||
| KEYWORDS; Antimalarial agent; Streptomyces | ||
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