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EFFCT OF ZINGIBEN OFFICINALE PLANT AND H2O2 ON SOME PHYSIOLOGICAL , HISTOLOGICAL AND BIOCHEMICAL PARAMETERS IN LOCAL MALE RABBITS | ||
| Mesopotamia Journal of Agriculture | ||
| Article 9, Volume 35, Issue 1, 2007, Pages 36-42 PDF (0 K) | ||
| DOI: 10.33899/magrj.2007.26468 | ||
| Authors | ||
| Muntaha Al– Kattan; Raja Al – Annaz; Iman Al– Sarrag | ||
| Dept. of Biology , College of Sci., Mosul Univ., Iraq | ||
| Abstract | ||
| This study was conducted to investigate the protective effect of Zingiben Officinale against the H2O2 induced oxidative stress in local male rabbits 5 – 6 months old . Rabbits were divided into 4 groups 4 rabbits each . Zingiben officinale was used as capsules at a dose of 1000 mg / kg. B. wt . The rabbits were treated dialy for 28 days . Oxidative stress was determined through measuring the levels of glutathione GSH and malondialdehyde MDA in liver tissue and of ALT and AST enzymes levels . H2O2 treatment showed significant decrease in liver tissue MDA and a significant increase liver tissue GSH serum AST and ALT were significantly increase also the above changes indicate the ability of H2O2 (1 %) in the induction of oxidative stress in local male rabbits .The treatment with zingiben officinale showed the following results significant decrease in ALT and AST serum levels , also significant decrease in liver tissue MDA and significant increase in GSH level , significant decrease in liver fat % These results indicate the protective effect of ZingibenOfficinal against oxidative stress . | ||
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