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EFFECT OF GARDEN CRESS (LEPIDIUM SATIVUM ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN WHITE MICE BONE MARROW CELLS | ||
| Mesopotamia Journal of Agriculture | ||
| Article 17, Volume 37, Issue 3, 2009, Pages 128-137 PDF (0 K) | ||
| DOI: 10.33899/magrj.2009.27436 | ||
| Author | ||
| Ilham A. Khalaf | ||
| Abstract | ||
| The effect of garden cress ( Lepidium sativum ) on mitotic index (MI) and formation of micronuclei (Mn) in bone marrow cells of white mice was studied , in addition to the study of the counter effect of plant juice on MI disruption and Mn induction by cyclophosphamide (Cp) . The results indicated that Cp reduced the MI to level of positive control after 2 , 4 , 6 days with significant differences compared to the negative control (P<0.01) , while the plant juice 0.1 , 0.25 , 0.5 ml / animal administrated orally had no effect and the MI values were similar to the negative control. Oral administration of juice before administration of the mutagen (R/Cp) or with the mutagen (R+Cp) helped the tissues to preserve their MI values at natural level. Administration of juice after the mutagen (Cp/R) resulted in reduction of MI values compared to the natural values with statistical significant difference (P<0.01) | ||
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