STUDIES ON HORMONAL CHANGES, HOMOCYSTEINE AND LIPIDS PROFILE IN IRAQI WOMEN WITH INFERTILITY

H. N. Al- Rubae, Salwa

	STUDIES ON HORMONAL CHANGES, HOMOCYSTEINE AND LIPIDS PROFILE IN IRAQI WOMEN WITH INFERTILITY
AL-TAQANI
Article 1, Volume 25, Issue 2, 2012, Pages 107-116
Author
Salwa H. N. Al- Rubae
Abstract
The cases of infertility have increased in women lately. The current study was conducted in order to obtain some indicators about the hormone changes, lipid profile and shedding light on the novel risk factor homocysteine which as considered as predictive and diagnostic factor of infertility. This study included 56 infertile women; in addition to 30 healthy women volunteers represented the control group, the study period was from December 2009 and April 2010. The results in this study revealed a high significant increase (P<0.0001) in BMI and the ratio of W/H in infertile women as compared to control group. The present study referred to significantly decrease)P <0.05) in the level of FSH and LH, and increase significantly (P< 0.0001) in LH/FSH ratio and prolactin. The present study show highly significant increase (P< 0.0001) in level of homocysteine as a risk factor in infertile women as compared to control group. The results also revealed to non significant increase in the level of cholesterol, TG and VLDL. While there was significant increase in LDL and significantly decrease in HDL. Results of the present study showed that important role of obesity, the increase in BMI, a decline in the level of sex hormones and increase in the level of homocysteine lead to infertility in women.

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