- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
SERUM LEVELS OF CALCIUM AND MAGNESIUM IN PATIENTS INFECTED WITH SCHISTOSOMA HAEMATOBIUM AND THOSE WITH BLADDER CARCINOMA | ||
| IRAQI JOURNAL OF MEDICAL SCIENCES | ||
| Article 1, Volume 5, Issue 1, 2007, Pages 17-21 | ||
| Authors | ||
| Tarik I. Al-Jeboori; Ameena S. M. Juma | ||
| Abstract | ||
| Background: Schistosomiasis is an ancient human disease with universal correlation between the endemicity of S. haematobium, genitourinary schistosomiasis and the frequency of bladder carcinoma. Calcium is the fifth most abundant mineral element in the human body and clearly correlated with T-cell activation. Magnesium is the fourth most abundant cation in the body with suggested a role of magnesium in the humoral antibody responses. Objective: To correlate the serum levels of calcium and magnesium during S. haematobium infection and the immunosuppression state associated with this disease in addition to their possible role in the development of bladder carcinoma. Methods: 200 individuals were included in this study (56 patients with acute schistosomiasis haematobium, 18 with chronic schistosomiasis, 20 with chronic schistosomiasis with bladder carcinoma, 50 with bladder carcinoma and 56 healthy controls). Venous blood was collected from each individual and the levels of calcium and magnesium were estimated in the serum of each individual. Results: Calcium levels were found to be significantly lower in patients with acute schistosomiasis and significantly higher in patients with chronic schistosomiasis with bladder carcinoma when compared to the healthy controls. No significant difference was found between the levels in patients with chronic schistosomiasis and the healthy controls. Magnesium levels were found to be significantly lower in patients with acute schistosomiasis, chronic schistosomiasis with bladder carcinoma and bladder carcinoma, whereas no significant difference was found in those with chronic schistosomiasis, when compared to the healthy controls. Conclusion: Because calcium and magnesium were found to be vital in the immune responses, the alteration in their levels might be one of the factors for the development of bladder carcinoma in patients with schistosomiasis. Key words: Schistosoma haematobium, calcium, magnesium, bladder carcinoma. | ||
| Keywords | ||
| Schistosoma haematobium; Calcium; magnesium; bladder carcinoma | ||
|
Statistics Article View: 160 PDF Download: 61 |
||