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STUDY OF THE LEPTIN LEVEL AND SOME IRON STATUS IN | ||
| AL-TAQANI | ||
| Article 1, Volume 24, Issue 7, 2011, Pages 86-96 | ||
| Authors | ||
| Zrar Saleem Marzany; Aydin S. Ahmad; Ismail S. Kakey | ||
| Abstract | ||
| placenta during pregnancy. The early indications that leptin might function in hematopoiesis arose from the cytokine characteristics of leptin and its receptor, the identification of leptin receptors in hematopoietic tissues. Aim:The objective of the present study is to investigate the effect of iron deficiency anemia on the levels of serum leptin. Subjects & Method:One hundred and twenty iron deficient, pregnant women at equal number of different gestation periods (40: 1st trimester, 40:2nd trimester, 40: 3rd trimester) were subjected to the study. Their ages were between 15-41 years. They were investigated at Maternity hospital in Arbil governorate from 1st January 2007 to 30th July 2007. Sixty healthy normal pregnant women at equal number of different gestation period were subjected to the study as a control group. Hemoglobin concentration, red blood cell indices (MCV and MCH), serum ferritin, serum iron, serum TIBC and serum level of leptin were estimated from each subjected women. Results:The mean values of serum leptin of anemic pregnant women were 20.18 1.702ng/ml, while the mean value of serum leptin of control (normal) pregnant women was 26.29 3.309 ng/ml. Statistical analysis revealed that Serum ferritn and serum iron levels were significantly (P< 0.001) decreased in iron deficient anemic pregnant women which reached 81.98 6.869 µg /dl and 21.36 2.946µg/l respectively. Serum total iron Binding capacity (TIBC) increased, but not statistically significant . The mean values reached 422.8 16.82 µg /dl in iron deficient anemic pregnant women. Conclusion: From the results of the study, we concluded that there were decreased in serum levels of leptin, iron and ferritin in pregnant anemic women, while total iron binding capacity increased. | ||
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