| The research was conducted to evaluate some hematological parameters during experimental infection with infectious bursal disease in broiler chickens . For this purpose 30 chicks were infected with the virus of the disease at 18 days old, whereas other 30 chicks were used as a control group . During the first and seventh day of the outbreak some hematological parameters were estimated which included packed cell volume , hemoglobin concentration and heterophil lymphocyte ratio as well as some biochemical tests such as serum protein , glucose, cholesterol , creatinine and uric acid , Aspartate Amino Transferase, Alanine Amino Transferase and Alkaline Phosphatase during the first and seventh day of infection with the virus. Results showed a significant reduction (P<0.05) of Packed Cell Volume (28.60%) and hemoglobin concentration (8.91gm100ml) in blood of infected birds and a significant increase (P<0.05) of HL (1.49) during the seventh day of infection . Infection caused a significant increase (P<0.05) of serum protein (10.14mg100ml) as well as a significant reduction (P<0.05) of serum glucose (168.60mg100ml) with a significant increase (P<0.05) of serum cholesterol (233.60mg100ml) during the seventh day of infection with the disease , whereas serum creatinine was not significantly differ between the infected and the control groups of chicks neither during the first nor the seventh day of infection , meanwhile , uric acid showed a high significant elevation (P<0.01) to become 10.80 mg100ml during the seventh day of infection . It was noticed that infection caused a significant elevation (P<0.05) of AST enzyme (23.0 IUL) during the first day of infection , however , ALT enzyme was not significantly differ between the infected and the control groups of chicks neither during the first nor the seventh day of infection , where as ALP enzyme was high significantly reduced (P<0.01) to become 60.80 and 63.40 IUL respectively during the first and seventh day of infection. |