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ALTERATION IN THE PHENOTYPE OF PERIPHERAL BLOOD T LYMPHOCYTE IN PATIENTS WITH IDIOPATHIC PRETERM LABOUR | ||
| IRAQI JOURNAL OF MEDICAL SCIENCES | ||
| Article 1, Volume 6, Issue 1, 2008, Pages 60-64 | ||
| Authors | ||
| Thoraya Hosaam Al-din; Nidhal Abdul-Muhymen; Maha M. Al-bayati | ||
| Abstract | ||
| Objective: The current study aimed to detect some changes occurred on the surface of T lymphocytes manifested by CD3, CD4 and CD8 molecules that may have a role in patients with idiopathic preterm labour. Setting: Al-Kadhimyia Teaching Hospital / Department of Obstetrics & Gynecology for a period of one year (March 2002-March 2003). Study design: Thirty patients with idiopathic preterm labour were enrolled in this study in addition to thirty healthy pregnant women as a control group. Blood samples were taken from both groups, lymphocytes were separated and immunofluorescent labeled by monoclonal antibodies to CD3, CD4 and CD8 surface markers. Results: Patients have a significant low percentage of these surface markers in comparison with control subject. Conclusion: The above findings confirm the suppression of cellular immunity in patients with idiopathic preterm labour. | ||
| Keywords | ||
| preterm labour; Lymphocytes; and CD | ||
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