- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
HISTOLOGICAL MODULATION OF ADULT RAT'S THYROID IN RESPONSE TO ANTI-OXIDANT FACTOR | ||
| IRAQI JOURNAL OF MEDICAL SCIENCES | ||
| Article 1, Volume 6, Issue 1, 2008, Pages 74-80 | ||
| Authors | ||
| A. A. Al-Taii; Hayder J. Mobarak; Samia A. Eleiwe | ||
| Abstract | ||
| Background: The pineal neurohormone namely melatonin regulates the bodily endocrine glands including thyroid gland, by controlling the function of pituitary gland. Objective: To study the effects of different doses of dietary melatonin (as antioxidant) on male rat's thyroid, "histologically". Methods: Melatonin was supplied to adult Wister albino rats, for successive 14 days. Rats were divided into 6 groups. Group I was the control. Group II, III, IV, V and VI were given a daily dose of 125, 250, 500, 750 and 1000 µg / kg body weight, respectively. After last day of treatment, animals were killed under effect of anesthesia and thyroid gland was taken for histological study. Results: The results showed no significant effects on thyroid with the regarded as normal therapeutic dosages, whereas significant damaging effects were seen with the higher doses. Conclusion: Dietary melatonin has no bad effect on adult rat's thyroid within therapeutic doses, but it had highly damaging changes in large doses. | ||
| Keywords | ||
| thyroid; Melatonin; anti; oxidant; and endocrine | ||
|
Statistics Article View: 186 PDF Download: 27 |
||