Zahra, , Abdul-Raheem Ahmed, A., hiah, , H. Ad, A., N. Jasim, A. (2010). The effect of calcium antagonists on the growth of Entamoeba histolytica in vitro. , 4(1), 5-10.
Zahra; a Abdul-Raheem Ahmed; hiah; Ali H. Ad; Amna N. Jasim. "The effect of calcium antagonists on the growth of Entamoeba histolytica in vitro". , 4, 1, 2010, 5-10.
Zahra, , Abdul-Raheem Ahmed, A., hiah, , H. Ad, A., N. Jasim, A. (2010). 'The effect of calcium antagonists on the growth of Entamoeba histolytica in vitro', , 4(1), pp. 5-10.
Zahra, , Abdul-Raheem Ahmed, A., hiah, , H. Ad, A., N. Jasim, A. The effect of calcium antagonists on the growth of Entamoeba histolytica in vitro. , 2010; 4(1): 5-10.

The effect of calcium antagonists on the growth of Entamoeba histolytica in vitro

Jornal of Biotechnology Research Center
Article 1, Volume 4, Issue 1, 2010, Pages 5-10
Authors
; a Abdul-Raheem Ahmed; ; Ali H. Ad; Amna N. Jasim
Abstract
he E. histolytica parasite was maintained in vitro using Locke-egg medium (LEM) and Liver infusion agar medium (LIAM). The effect of two calcium antagonists (Nifedipine and Ethylene-diaminetetraacetic acid EDTA) on the growth and activity of the parasite in the two culture media was investigated. The calcium antagonists Nifedipine and EDTA inhibited the reproduction rate of E. histolytica in a concentration-dependent manner. For Nifedipine, a concentration of 41.6 mg/ml inhibited the reproduction rate to 99.7% in both media. The EDTA had an approximate effect (98.2 and 95.8)% at a concentration of 0.83 mg/ml in LEM and LIAM media, respectively. Additionally, some cases of a parasite encystment were observed in LEM medium that was treated with Nifedipine.
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