- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
A STUDY FOR THE CORRELATION BETWEEN EOSINOPHIL DERIVED NEUROTOXIN (EDN) AND ASTHMA | ||
| IRAQI JOURNAL OF MEDICAL SCIENCES | ||
| Article 1, Volume 7, Issue 2, 2009, Pages 67-74 | ||
| Authors | ||
| Amer Al-Najjar; Nidhal Abdul-Mohymen; | ||
| Abstract | ||
| Background: Eosinophil Derived Neurotoxin (EDN) has been used to assess eosinophil cells activity and to monitor inflammation in asthmatic patients. Objective: Study the correlation between Eosinophil Derived Neurotoxin (EDN) and asthma. Materials and methods: Eosinophil Derived Neurotoxin (EDN) was extracted from eosinophils taken from patients with eosinophilic leukemia.This extract was conducted to study its biological effects (Gordon phenomena) and detection of antibodies against it in urine samples of diagnosed asthmatic patients. Results: One of the two tested rabbits with the extracted EDN test material showed the signs and symptoms of Gordon phenomenon during the second day after injection and continued to show complete paralysis within the fifth day .Patients urine results showed that it contained a higher values of END than the control subjects urine . Conclusion: Results revealed that EDN is a product that can be used as a monitor for asthma. Key words: EDN, asthma, ELISA. | ||
| Keywords | ||
| eosinophil derived neurotoxin; EDN; asthma; ELISA | ||
|
Statistics Article View: 210 PDF Download: 29 |
||