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The histochemical effects of the administration of hydrocortisone sodium succinate upon the periodontium of albino rats' experimental study | ||
| Journal of baghdad college of dentistry | ||
| Article 1, Volume 17, Issue 2, 2005, Pages 59-63 | ||
| Author | ||
| Asmaa S. Al-Douri | ||
| Abstract | ||
| Background: The effects of the administration of cortisone upon numerous body tissues have been described; changes in the periodontal tissue of developing albino rats (newborn) histochemically have not been described. A study was therefore, under taken to investigate the effect of administration of cortisone upon the periodontal ligament tissues. Materials and methods: Experimental animals (new born rats, their age 10, 19, 25 days old) were treated by cortisone, saggital sections were stained by alcian blue and H&E stains. Results: It was shown that the hydrocortisone sodium succinate affect that periodontal tissue development and this drug inhibit and delay the synthesise of GAGs (glycosaminoglycans) till aged 25 post natal (p.n.). Conclusion: The periodontal membrane in the treated groups is affected (delay in the GAGs synthesis) by the hydrocortisone sodium succinate drug administration | ||
| Keywords | ||
| Hydrocortisone; periodontal ligament; alcian blue | ||
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