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The relationship between the severity of gingival inflammation and the concentration of the gingival fluid proteins | ||
| MUSTANSIRIA DENTAL JOURNAL | ||
| Article 1, Volume 8, Issue 3, 2011, Pages 335-342 | ||
| Authors | ||
| ; Dr. Barzan Al-Atrooshi B.D.S; Dr. Alaa Omran Al-mosawi B.D.S; ; Dr. Khulood Al-Safi B.D.S. M.Sc. Ph.D | ||
| Abstract | ||
| The gingival fluid flow occur when the gingival tissue and vessels are irritated. In a chronically inflamed gingiva the blood-tissue barrier is no longer intact, an increased permeability exists which permits a leakage of plasma protein into the intervascular tissue, the affected blood vessels exhibits qualitative changes of the vascular wall these include the formation of non selective fenestrations which permit exudation of the whole plasma proteins. Most of these proteins are involved in the mechanisms initiating and controlling the inflammatory response. The aims of this study is to provide information about some aspect of proteins in the gingival fluid during inflammation .Seven plasma proteins of different molecular weight chosen for assay: Haptoglobine, alpha-1 glycoprotien, orosomucoid, prealbumin, alpha-1 antitrypsin, IgG, IgA and IgM. Thirty subjects selected for investigation, the gingival fluid collected by micropipettes from the gingiva adjacent to the upper anterior teeth, clinical assessment of the gingival condition made according to the gingival index GI of Loe and Silness then the patients divided into three groups. Concentration of the proteins determined by using laser nephelometry. Demonstrate a remarkable difference in the rate of gingival fluid flow with higher flow rate in cases with chronically inflamed gingiva, the concentration of the proteins increase with the severity of the gingival inflammation . In conclusion the concentration of the proteins are not related to their molecular weight and lasernephelometry seems to be a reliable technique for screening studies of gingival fluid proteins. | ||
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