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Assessment of Endometrial Thickness in Postmenopausal Women with and without Hypertension | ||
| Iraqi Postgraduate Medical Journal | ||
| Article 1, Volume 11, Issue 1, 2012, Pages 39-44 PDF (0 K) | ||
| Author | ||
| Nada Salih Amen | ||
| Abstract | ||
| ABSTRACT : BACKGROUND: Hypertension in postmenopausal women is a risk factor for endometrial hyperplasia. OBJECTIVE: To examine whether the endometrium of hypertensive postmenopausal women is thicker than that of non hypertensive postmenopausal women, to determine whether this thickening is directly related to the antihypertensive drugs and whether is associated with abnormal pathology. METHODS: A Case control study of Forty five hypertensive asymptomatic postmenopausal women was conducted in Al Yarmouk Teaching Hospital, (22) were treated with B- blockers combination medication and (23) were treated with other medications. They were compared with each and with (25) non hypertensive women. All women were interviewed; blood tests were performed and endometrial thickness in antero-posterior diameter was measured by vaginal ultrasonography. Endometrial sampling had been taken for those with increased endometrial thickness more than 5mm. RESULTS: 24.44% of hypertensive women and 4.00% of non hypertensive women had an endometrial thickness more than 5mm. There was no statistically significant difference between those who treated with medication including B- blocker and those who were treated with other medication. The histological findings were mainly of endometrial hyperplasia for those with thickened endometrium. CONCLUSION: Hypertension may have a role in endometrial thickness. We were unable to substantiate an association between the type of treatment administered and the increase in endometrial thickness. Those with increased endometrial thickness more than 5mm, the histological findings were mainly of endometrial hyperplasia | ||
| Keywords | ||
| Hypertension; menopausal women; endometrial hyperplasia | ||
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