R. Waleed, S., R. Wafa, A., A. Mohammed, T. (2006). Effect of metformin and antioxidant agents on oxidative stress status and follicular maturation in women with polycystic ovary syndrome. , 3(1), 40-45.
Sulaiman R. Waleed; Al-Omari R. Wafa; Taher A. Mohammed. "Effect of metformin and antioxidant agents on oxidative stress status and follicular maturation in women with polycystic ovary syndrome". , 3, 1, 2006, 40-45.
R. Waleed, S., R. Wafa, A., A. Mohammed, T. (2006). 'Effect of metformin and antioxidant agents on oxidative stress status and follicular maturation in women with polycystic ovary syndrome', , 3(1), pp. 40-45.
R. Waleed, S., R. Wafa, A., A. Mohammed, T. Effect of metformin and antioxidant agents on oxidative stress status and follicular maturation in women with polycystic ovary syndrome. , 2006; 3(1): 40-45.

Effect of metformin and antioxidant agents on oxidative stress status and follicular maturation in women with polycystic ovary syndrome

Al-Mustansiriyah Journal for Pharmaceutical Sciences
Article 1, Volume 3, Issue 1, 2006, Pages 40-45
Authors
Sulaiman R. Waleed; Al-Omari R. Wafa; Taher A. Mohammed
Abstract
In this study, forty-two Iraqi Arab Women with PCOS were involved and they were classified into
three groups according to type of treatment:
1) Group І: fourteen patients who administered metformin (500mg t.i.d).
2) Group П: fourteen patients who administered combination of metformin (500mg t.i.d) with vitamin
C (250mg t.i.d)
3) Group PI: fourteen patients who administered combination of metformin (500mg t.i.d) with
vitamin E (200mg t.i.d).All groups were treated for three months .
The present study includes the measurement of serum malondialdehyde, Vitamin E and its metabolite
(tocopheronic acid) play an important role in alleviation of oxidative stress(MDA) and may potentiate
the metformin activity in maturation of follicles
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