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THE ACTION OF IRAQI PROPOLIS ON THESPECIFIC ACTIVITY OF ADENOSINE DEAMINASEENZYME IN ALBINO MICE | ||
| Iraqi Journal of Biotechnology | ||
| Article 1, Volume 7, Issue 1, 2008, Pages 110-116 | ||
| Abstract | ||
| ABSTRACTThe action of propolis in the specific activity of adenosine deaminase (ADA; EC3.5.4.4) in albino mice was investigated. Two oral administrations (10 and 20mg/kg/day) of Iraqi propolis extract with two control groups were used. Treatmentwith propolis enhanced the specific activity of ADA enzyme in serum, thymus andspleen as compared to control groups; the stimulation was greater at the higherdose. While, treatment with Mitomycin C; MMC (positive control) under similarcondition caused a highly significant inhibition in activity of ADA in serum,thymus and spleen as compared to negative control. This study indicates that Iraqipropolis extract may potentiate immunity with the modulation of adenosinergicsystem through increasing splenic and thymic ADA enzyme activity.KeyWords: Propolis, adenosine deaminase, mitomycinC | ||
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