- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
DETECTION OF RESPIRATORY SYNCYTIAL VIRUS INFECTION IN A SAMPLE OF INFANTS IN IRAQ | ||
| IRAQI JOURNAL OF MEDICAL SCIENCES | ||
| Article 1, Volume 7, Issue 4, 2009, Pages 11-19 | ||
| Authors | ||
| Nahi Y. Yaassen; Anton S. Al-Bana; Shony M. Odisho | ||
| Abstract | ||
| Background: Human Respiratory syncytial virus (HRSV) is one of the major causes of bronchiolitis and pneumonia in infants. Objective: detection of Anti HRSV antibodies in infants and children by using indirect ELISA, and detection of HRSV antigen by using Respi- RSV test. Materials and Methods: Hundred and eighty four serum samples (104 with respiratory tract infection, 54 without Respiratory tract infection, and 26 with cancer) also 100 nasal and throat swabs were collected from infants and children from Central Pediatric Hospital in Baghdad in year (2005-2006). Indirect ELISA test and rapid test used for detection Human RSV antibodies and Human RSV antigen respectively Results: Detection of anti HRSV antibodies using ELISA in children without respiratory tract infection was 26% with mean titer 494, but the antibodies was higher in patients with cancer which were 96% with mean titer 580, however anti HRSV was detected in79% in infants with respiratory tract infection (bronchiolitis and pneumonia), their mean titer (1411) was, higher than that of the previous two groups. Human RSV viral antigen was detected by RSV-Respi kit in 45% of nasal and throat secretion collected from children with respiratory tract infection, detection of HRSV antigen samples was compatible with the detection of antiHRSV antibodies in 50%. Conclusion: The highest percentage and titers of antiHRSV antibodies were detected in infants with respiratory tract infection than in others suffering from different cancers or without respiratory tract infection. Human RSV antigens were detected in nasal/throat swabs in infants with bronchiolitis and pneumonia. Keywords: Respiratory syncytial virus, bronchiolitis, Respi-RSV. | ||
| Keywords | ||
| Respiratory syncytial virus; bronchiolitis; Respi; RSV | ||
|
Statistics Article View: 158 PDF Download: 76 |
||