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Relationship between postprandial hyperglycaemia and Progression of Diabetic Nephropathy | ||
| Al-Qadisiah Medical Journal | ||
| Article 1, Volume 2, Issue 1, 2007, Pages 124-132 PDF (0 K) | ||
| Authors | ||
| Hazem K. Abdul-Kareem; Ali S.Abdul-Razzaq Al-hilli | ||
| Abstract | ||
| BACKGROUND: With the recent development of new methods to measure postprandial hyperglycemia and new treatments to modulate it, investigators have questioned whether postprandial hyperglycemia causes diabetic complications such as nephropathy. OBJECTIVES: the aim of our study was to assess the influence of postprandial hyperglycaemia on the incidence of nephropathy in patients with type 2 diabetes.) Patients&METHODS: 112 patients attending diabetic clinic in Al-diwanyia teaching hospital fulfilled the criteria of the study. The patients investigated for macroalbuminuria. The patient divided into two groups according to the result of 2 successive measurements of post-challenge plasma glucose level (following 75 gm glucose solution )2 weeks apart . RESULTS: Of total 112 patients with mild-moderate type 2 diabetes for last 5-7 years, about84 patients(75%) had postprandial plasma glucose values>200 mg/dl, 69(82.1%) patients of them had macroalbuminuria,whereas macroalbuminuria observed in 6 patients only ( 25 % of total ) in those with postprandial plasma glucose < 200 mg / dl total ). Macroalbuminuria reported in 7 patients (of the total 112) had normal FPG. | ||
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