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Some Polarographic behaviour of ambilhur drug in different media (vitro) | ||
| Iraqi National Journal Of Chemistry | ||
| Article 1, Volume 0, Issue 41, 2014, Pages 106-112 | ||
| Author | ||
| Faris H. Abdul Razzak | ||
| Abstract | ||
| Abstract The polarographic behaviour of ambilhur (niridazole) [1-(5-Nitro-2-thiazolyl)-2-imidazolidinone(I)] have been studied. The drug give a well sensitive defined single peak at about -0.45V in carbonate buffer solution at pH 7.4 and -0.46V in serum-carbonate buffer and at -0.34V in urine-carbonate buffer. The lowest determined concentration in aqueous carbonate buffer 9.1×10-7 M , in serum-carbonate buffer media was 5.4×10-7 M and 3.2×10-7 M in urine-carbonate media with correlation coefficient 0.998, 0.996, 0.999. the relationship between concentration and diffusion current Ip was linear for all solutions. | ||
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