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Effects of the Aqueous Extract of the of Cinnamonum zeylanicum Barks (Cinnamon) on Glucose, Haemoglobin and Lipid Profile in Alloxan – Induced Diabetic Rats | ||
| Journal of University of Babylon | ||
| Article 1, Volume 17, Issue 1, 2009, Pages 17-22 | ||
| Authors | ||
| Shahbaa M. Al-Khazraji; Zena K. Khalil | ||
| Abstract | ||
| Abstract Cinnamonum zeylanicum (cinnamon) bark is considered extensively in the endogenous system of medicine as a drug for diabetes in many countries . The current investigations focuses attention on the glucose and lipid lowering effect of the aqueous extract of Cinnamonum zeylanicum (cinnamon) barks on experimentally induced diabetes in rats . The biochemical parameters studied were plasma glucose, insulin , total cholesterol, triglycerides, phospholipids, mhaemoglobin, and glycosylated haemoglobin. In addition to measuring body weight , renal glucose reassertion were notified. Aqueous extract of cinnamon barks were orally administered daily for 30 days in a dose of 100 mg / kg body weight to alloxan– diabetic rats, and a significant reduction in the parameters measured was investigated compared to diabetic rats, meanwhile , Glibinclamise was used as standard reference drug. In conclusion cinnamon barks posses a hypoglycaemic with concurrent hypolipidemic effect in diabetic states , and may further suggests that cinnamon parks may be useful in the therapy and managements of diabetic hyperlipidemia through reducing lipids levels. | ||
| Keywords | ||
| Alloxan; diabetes mellitus; hyperlipidemia; Cinnamonum zeylanicum | ||
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