Hamed Abed, H., A.K, , Ismaiel, , Al-Ezzi, I., Muthanna, , Abdulkarim, H., Abass Al-shami, A., K. Jabbar, A., L. Shaymma, S., B. Dalya, H., H. Amal, S., M. Mahmoud, M., A. Abd-Alrahman, S., A. Suraf, H., A. Ghaith, A., H. Amal, S., A.Muhieldeen, S., R. A. AL-Shuaibi, A., M. Lateef, S., J. Al-Jeboori, M. (2008). Evaluation of testosterone and prolactin hormones levels in erectile dysfunction patients after single oral dose of Tadalafil. , 5(1), 52-60.
Hayder Hamed Abed; A.K; Ismaiel; I. Al-Ezzi; Muthanna; HushamM. Abdulkarim; Adeeb Abass Al-shami; Alaa K. Jabbar; Salman L. Shaymma; Hana B. Dalya; Salman H. Amal; Mahmoud M. Mahmoud; Shermean A. Abd-Alrahman; Hussain A. Suraf; Al-Zubaidy A. Ghaith; Salman H. Amal; Samir A.Muhieldeen; A. R. A. AL-Shuaibi; S. M. Lateef; M. J. Al-Jeboori. "Evaluation of testosterone and prolactin hormones levels in erectile dysfunction patients after single oral dose of Tadalafil". , 5, 1, 2008, 52-60.
Hamed Abed, H., A.K, , Ismaiel, , Al-Ezzi, I., Muthanna, , Abdulkarim, H., Abass Al-shami, A., K. Jabbar, A., L. Shaymma, S., B. Dalya, H., H. Amal, S., M. Mahmoud, M., A. Abd-Alrahman, S., A. Suraf, H., A. Ghaith, A., H. Amal, S., A.Muhieldeen, S., R. A. AL-Shuaibi, A., M. Lateef, S., J. Al-Jeboori, M. (2008). 'Evaluation of testosterone and prolactin hormones levels in erectile dysfunction patients after single oral dose of Tadalafil', , 5(1), pp. 52-60.
Hamed Abed, H., A.K, , Ismaiel, , Al-Ezzi, I., Muthanna, , Abdulkarim, H., Abass Al-shami, A., K. Jabbar, A., L. Shaymma, S., B. Dalya, H., H. Amal, S., M. Mahmoud, M., A. Abd-Alrahman, S., A. Suraf, H., A. Ghaith, A., H. Amal, S., A.Muhieldeen, S., R. A. AL-Shuaibi, A., M. Lateef, S., J. Al-Jeboori, M. Evaluation of testosterone and prolactin hormones levels in erectile dysfunction patients after single oral dose of Tadalafil. , 2008; 5(1): 52-60.

Evaluation of testosterone and prolactin hormones levels in erectile dysfunction patients after single oral dose of Tadalafil

Al-Mustansiriyah Journal for Pharmaceutical Sciences
Article 1, Volume 5, Issue 1, 2008, Pages 52-60
Authors
Hayder Hamed Abed; ; ; I. Al-Ezzi; ; HushamM. Abdulkarim; Adeeb Abass Al-shami; Alaa K. Jabbar; Salman L. Shaymma; Hana B. Dalya; Salman H. Amal; Mahmoud M. Mahmoud; Shermean A. Abd-Alrahman; Hussain A. Suraf; Al-Zubaidy A. Ghaith; Salman H. Amal; Samir A.Muhieldeen; A. R. A. AL-Shuaibi; S. M. Lateef; M. J. Al-Jeboori
Abstract
Erectile dysfunction (ED) is defined as a consistent inability to sustain an
erection sufficient for sexual intercourse. Tadalafil is a selective, reversible
inhibitor of cyclic guanosine monophosphate (cGMP)-specific
phosphodiesterase type 5 (PDE5). When sexual stimulation causes the local
release of nitric oxide, inhibition of PDE5 by tadalafil produces increased levels
of cGMP in the corpus cavernosum. This results in smooth muscle relaxation
and inflow of blood into the penile tissues, thereby producing an erection.
Tadalafil has no effect in the absence of sexual stimulation. Erection
dysfunction could attribute abnormal levels of testosterone and prolactin levels.Twenty Iraqi patients with different levels of ED were considered in this
study treated with 20 mg. of tadalafil coated tablets. All patients considered in
this study have been get erection after treatments with tadalafil. Prolactin and
testosterone has been determined by radioimmunoassay (RIA). The evaluated
results indicated significant decrease for prolactin (p<0.01) and significant
elevation for the testosterone (p

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