- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Evidence of Correlation between Some Auto Antibodies with Complement Component in Lupus Nephritis | ||
| Iraqi Postgraduate Medical Journal | ||
| Article 1, Volume 6, Issue 1, 2007, Pages 54-57 PDF (0 K) | ||
| Authors | ||
| Nawar Abass Abud Noor; Kholod Daher Habib Al-Shemari; Lilyan W. Sersam; Ibtesam Ghadhban Auda; Nada Khadum Al- Tae; Aroub Abdul Rahman Al-Kaisi | ||
| Abstract | ||
| ABSTRACT: BACKGROUND: lupus nephritis is a fatal complication of systemic lupus erythematosus (SLE), the serological hallmark of SLE is the presence of circulating autoantibodies directed against a wide variety of nuclear, cytoplasmic and plasma membrane antigens among which are anticardiolipin (ACL),anti-B2glycoprotein and anti-C1q antibodies, together with the consumption of complement component (C3 &C4) by immune complex mediated reaction. AIM OF STUDY: To shed light on the relations among these autoantibodies and with complement component in lupus nephritis patients. METHODS: Tthe study was conducted on 25 patients with lupus nephritis, attended the renal clinic in specialized surgical hospital/ medical city /Baghdad, 25 lupus patients without nephritia and 25 healthy controls. Enzyme linked immunsorbant assay was used for detection for ACL, anti-B2GP, anti-C1q, while single radial immundiffusion plates used for the estimation of C3& C4. RESULTS AND CONCLUSION: Anticardiolipin antibodies correlated significantly with anti-B2GP IgG & IgM (P<0.05), anti-C1q antibodies (P Keywords Autoantibodies --- C3 --- C4 complement --- lupus nephritis. | ||
| Keywords | ||
| Autoantibodies; complement; lupus nephritis; Pregnancy; Ectopic; Colour Doppler; Transvaginal ultrasound; Cyclophosphamide; Doxorubicin; Methotrexate; Ciprofloxxacin resistance; Uropathogenic Escherichia coli; Mutation; Leukemia; Liquefied propane gas; Oxidative stress; lipid peroxidation; antioxidant enzymes; Intestinal parasitosis; intestinal parasitic infections; intestinal protozoa | ||
|
Statistics Article View: 402 PDF Download: 111 |
||