- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
THE POSSIBLE PROTECTIVE ROLE OF BCL-2 IN RECURRENT ABORTION | ||
| IRAQI JOURNAL OF MEDICAL SCIENCES | ||
| Article 1, Volume 8, Issue 3, 2010, Pages 49-54 | ||
| Author | ||
| Haider Sabah Kadhim | ||
| Abstract | ||
| Background: Recurrent abortion is a worldwide problem, with undefined causes. Apoptosis could play a major role in the process. Objective: Detect the expression of Bcl-2 protein at the materno-fetal interface in patients with recurrent pregnancy loss (RPL). Methods: Immunohistochemistry analysis of Bcl-2 protein using paraffin embedded sections of curate samples obtained from 40 women divided into three groups: 24 women with recurrent abortion, 10 women with abortion for the first time, and 6 women with induced abortion. Results: The mean value of the expression of Bcl-2 protein was (57.9± 1.4), which is significantly higher than that of the second group (39± 1.9), and the third group (47.5± 2.4). Conclusion: High expression of Bcl-2 protein in women with recurrent abortion may have a protective role in preventing placental apoptosis that leads to failure of pregnancy. Keywords: Bcl-2, recurrent pregnancy loss (RPL). | ||
| Keywords | ||
| Bcl; recurrent pregnancy loss; BCL | ||
|
Statistics Article View: 35 PDF Download: 4 |
||