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Sex-Pheromone System and Plasmid Transfer in Enterococcus feacalis | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 8, Issue 1, 2011, Pages 0-0 | ||
| Author | ||
| Jawad Kadhum Tarrad Al-Khafaji | ||
| Abstract | ||
| Pheromone-inducible plasmid transfer is an important mechanism for dissemination of antibiotic resistance and virulence factors in these organisms. Plasmid-free strains of Enterococcus faecalis secrete at least half a dozen peptide sex pheromone-probably many more-that induce a mating response by potential donor strains carrying members of specific families of conjugative plasmids. The response is associated with synthesis of surface proteins that facilitates formation of donor-recipient mating aggregates. When a recipient acquires a given plasmid , the corresponding pheromone becomes shutdown or masked. Although the structure of at least five of these peptides has been determined. | ||
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