M. Ali, A., T. Barakat, N., H. Obaid, H., A.Hassan, A., A. Abaas, Z. (2010). CYTOTOXICITY EFFECT OF AQUEOUS EXTRACT OF BRASSICA RAPA ROOTS ON CANCER CELL LINES IN VITRO. , 51(4), 550-560.
Amal M. Ali; Nadia T. Barakat; Hind H. Obaid; Aiman A.Hassan; Zainab A. Abaas. "CYTOTOXICITY EFFECT OF AQUEOUS EXTRACT OF BRASSICA RAPA ROOTS ON CANCER CELL LINES IN VITRO". , 51, 4, 2010, 550-560.
M. Ali, A., T. Barakat, N., H. Obaid, H., A.Hassan, A., A. Abaas, Z. (2010). 'CYTOTOXICITY EFFECT OF AQUEOUS EXTRACT OF BRASSICA RAPA ROOTS ON CANCER CELL LINES IN VITRO', , 51(4), pp. 550-560.
M. Ali, A., T. Barakat, N., H. Obaid, H., A.Hassan, A., A. Abaas, Z. CYTOTOXICITY EFFECT OF AQUEOUS EXTRACT OF BRASSICA RAPA ROOTS ON CANCER CELL LINES IN VITRO. , 2010; 51(4): 550-560.

CYTOTOXICITY EFFECT OF AQUEOUS EXTRACT OF BRASSICA RAPA ROOTS ON CANCER CELL LINES IN VITRO

Iraqi Journal of Science
Article 1, Volume 51, Issue 4, 2010, Pages 550-560
Authors
Amal M. Ali; Nadia T. Barakat; Hind H. Obaid; Aiman A.Hassan; Zainab A. Abaas
Abstract
Effect of aqueous extract of Brassica rapa roots on three types of cancer cell lines; Hep-2, AMN-3 and Hela was studied in vitro.
The results showed that, the cytotoxic effect of extract dependent on type of cells, amount of dose and exposure time.
The concentration 1250 µg/ml gave higher growth inhibition , were ( 63 and 42 ) % to ANM-3 and Hep-2 respectively comparied with control 100% after 24 hours from exposure time , but inhibition gowth of Hela cells was 64% by 10000 µg/ml crud roots extract for 24 hours.
Exposure time for 48 hours reduced the percentage of inhibited growth٫ only by 10000 µg/ml for extract; viability was 25 % for ANM-3 cells.
Crud aqueous extract of Brassica rapa roots was have hormetic effect ( Hormesis ), because also induced the proliferation of cancer cells by used low concentration of extract after 72 hours exposure time.
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