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Systemic Treatment Of Murine Mammary Adenocarcinoma Transplanted Subcutaneously In Mice By Virulance Newcastle Disease Viruse | ||
| Kufa Journal For Veterinary Medical Sciences | ||
| Article 1, Volume 1, Issue 2, 2010, Pages 19-31 | ||
| Authors | ||
| AbdulAmeer O. Ismail; T. A. Makkawi; Nahi Y. Yaseen; Anton S. Albana | ||
| Abstract | ||
| Abstract: The present study included of six groups of femals mouse injecting with cells from murine mammary adenocarcinoma subcutaneously, three groups as treated and the others as control groups. The first group, Which was treated with BCG and injection of virulence Newcastle disease virus(NDV) intraperitonealy (I.P),showed prominent suppression of tumor statistically significant with ( 53 % ) compared with group of negative control and (46%) compared with group of positive control . The groups treated with (NDV),shown increase of relative tumor volume(RTV) compared with tumor size at the start of treatment but these increased lower than increased will be occurs in untreated groups. Grossly,The treated tumor characterized by small in size,firm compared with tumor size in untreated groups.Histopathological examination of the treated tumor showed wide areas of necrosis associated with lymphocytic ,plasmic and macrophagic infiltration. | ||
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