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HER-2/neu Expression in Colorectal Carcinoma and its Correlation with Pathological Parameters by Immunohistochemistery | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 8, Issue 2, 2011, Pages 253-262 | ||
| Author | ||
| Shoroq Mohamed Abas Al-Temimi | ||
| Abstract | ||
| This study was conducted to estimate the expression of her2/neu oncoprotein in human colorectal carcinoma and to show its possible correlation to the pathological parameters. Thirty five patients of colorectal carcinoma were studied in Al- Diwanyia teaching hospital and some private hospital in a period from January 2007 to Juan 2010 , out of 35 cases there were only 20cases positive for her2/neu oncoprotein. The rate of her2 was high in colorectal carcinoma and the important feature of her2/neu expression was the membranous-cytoplasmic pattern , it was prominent in Grade III ,and stages C and D , so this pattern indicates poor prognosis of the tumor. | ||
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