- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
A high sensitive colorimetric assay for the determination of dopamine hydrochloride in pharmaceutical preparationsUsing charge transfer complex reaction. | ||
| Iraqi National Journal Of Chemistry | ||
| Article 1, Volume 0, Issue 37, 2014, Pages 60-65 | ||
| Authors | ||
| Abdul Barry Mahdi Mahood; Mohammed Jassim Hamzah | ||
| Abstract | ||
| Abstract A simple , rapid and sensitive spectrophotometric method for the determination of trace amounts of dopamine hydrochloride in aqueous solution is described. The method is based on a reaction between dopamine hydrochloride with the mixture of Fe+3 and hexacynoferrate(III) ions to form an intense Prussian blue color complex that has a maximum absorption at 710nm with a molar absorptivity of 2.138x104l.mole-1. cm-1 and a sandell sensitivity of 8.862x10-6µg.cm-2. Under optimum reaction conditions the absorbance of the Prussian blue color complex were found to increase linearly with increase in concentration of dopamine hydrochloride in the range (0.4-12ppm) with a relative standard deviation of 0.138-0.350% and a relative error of -1.983 to 2.9%. The proposed method was successfully applied for the determination of the selected drug in pharmaceutical preparations with very good recoveries of 98.02- 103.02%. | ||
|
Statistics Article View: 157 PDF Download: 149 |
||