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A Study of Some Haemato-Physiological Changes in Patients with Diabetic Nephropathy | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 8, Issue 3, 2011, Pages 461-475 | ||
| Authors | ||
| Muhammad O. Al-Muhammadi; Sura Mouayad Alwash | ||
| Abstract | ||
| Diabetic nephropathy is a leading cause of DM-related morbidity and mortality. Pathogenesis of diabetic nephropathy is related mostly to chronic hyperglycemia. The study was designated to estimate some possible risk factors of diabetic nephropathy and assessed clinically , haematologically the patients with diabetic nephropathy, since the changes in these parameters are important in detecting, quantifying, identifying some possible risk factors and assessing patient’s response to treatment. The patients and controls enrolled in this study had undergone full assessment that included:- clinical assessment by history and examination, haematological assessment (measurement of RBCs counts, blood Hb and PVC and RBCs indices), hormonal study(serum erythropoietin level). The study revealed that diabetic nephropathy prevalence more in female with long duration of DM. In regard to haematological parameters the results of study show that there is highly significant decreased (p< 0.01) in RBCs counts, blood Hb, PCV and RBCs indices , as well as serum erythropoietin in diabetic nephropathy patients in compare to control groups. In conclusion, diabetic nephropathy associated with increased and decreased in some hematological parameters may be attributed to anemia that accompany diabetic nephropathy. | ||
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