Xanthine Oxidase Activity as an Index of lipid Peroxidation in  Sera of Patient with Mayocardial Infraction in Erbil City  Population

Rostom Ali, Deler; Jalil Mahmood, Tayfor; G Hasan, Hamid

	Xanthine Oxidase Activity as an Index of lipid Peroxidation in Sera of Patient with Mayocardial Infraction in Erbil City Population
Medical Journal of Babylon
Article 1, Volume 7, Issue 3, 2010, Pages 431-438
Authors
Deler Rostom Ali; Tayfor Jalil Mahmood; Hamid G Hasan
Abstract
Acute mayocardial infarction (MI) remains a leading cause of morbidity and mortality world wide. MI occurs when myocardial ischaemia exceeds a critical threshold and overwhelms mayocardial cellular repair mechanisms designed to normal operating functions and homostatus. Activity of xanthine oxidase (XO), MDA and vit-C concentrations were determined in sera of 100 patients with MI. Their mean±SD age was (57.05±1.25) year. The same parameters were determined in sera of 100 apparently healthy matched subjects as a control group. The mean ±SE of XO, MDA, and vit-C in patients with MI was 0.031±0.016 unit/ mg protein, 1.28±0.053 µ mol/L, 0.520±0.137 mg/dl respectively while the mean ± SE of control group was 0.012±0.006 unit/ mg protein, 0.819±0.019 µ mol, and 0.648±0.302 mg/dl respectively. There were significant differences in the mean value of XO and MDA in patient with MI compared to control group (P<0.001). However the mean value of vit-C showed no significant differences in both groups.

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