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The Effect of Combined Oral Contraceptive Pills and Copper Bearing Intrauterine Contraceptive Devices on The Oxidative Stress, Lipid Profile and Some Trace Elements in Women Sera in Hilla City | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 7, Issue 3, 2010, Pages 490-498 | ||
| Authors | ||
| Moaed E. Al-Gazally; Melal M. Al-Jeborry; Ghufran M. Al-Asadi | ||
| Abstract | ||
| The study was conducted on sixty three healthy women used combined oral contraceptive pills (COCPs) and copper bearing intrauterine contraceptive devices (IUDs). Thirty women were used Microgynon R (low dose COCPs, each pill containing levonorgestrel 0.15 mg and ethinyl estradiol 0.03 mg) and thirty three women used copper T 380A IUDs. Thirty apparently healthy women were taken as control group. Blood samples obtained from women used contraceptives and control group from Babylon maternity and pediatric hospital in Hilla city. The sera obtained from the blood were used to determine the effect of COCPs and IUDs on of malondialdehyde (MDA), total cholesterol, high density lipoprotein (HDL), triglycerides (TGs), very low density lipoprotein (VLDL), low density lipoprotein (LDL) and some trace elements (copper, zinc and iron) concentration. The results of the present study showed (significant increase in MDA, copper, iron, total cholesterol, TGs, VLDL and LDL concentration), significant decrease in HDL and non significant decrease in zinc concentration in sera of women who used COCPs when compared to both women who used IUDs and the control group. Also this study showed non significant difference in MDA, copper, zinc, total cholesterol, HDL, TGs, VLDL and LDL concentration and significant decrease in iron concentration in sera of women who used IUDs when compared to those of the control group. | ||
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