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Detection of Multidrug resistant Pseudomonas aeruginosa Isolates producing IMP-1 Metallo-ß-Lactamase in some Baghdad hospitals | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 15, Issue 1, 2010, Pages 188-192 | ||
| Authors | ||
| Mohammed F. AL- Marjani; Makarim A. Khalil; Zina H. Jazar | ||
| Abstract | ||
| This Study describe the Molecular characterization of a Multiresistant Pseudomonas aeruginosa isolates in three hospitals in Baghdad ( Central Child hospital , Central Medicine City hospital and Al-Noman hospital). Analysis included antimicrobial susceptibility profile and Plasmid profile Bacterial isolates were tested against (11) antimicrobial agents: Imipenem, Ciprofloxacin, Aztreonam, Cefuroxime, Amoxicillin, Cefotaxime, Nalidixic acid , Trimethoprim, Tetracycline, Mezlocillin and Gentamicin. Results showed that all the isolates were resistant to Cefuroxime , Amoxycillin , and Tetracycline , and all the isolates have showen multiple resistance for antibiotics. The majority of isolates remained susceptible to Imipenem (22%) . Our results showed also that 9 isolates ( 18 %) had the ability to produce Metallo ß -lactamase enzymes (MßLs) . On the other hand, DNA analysis ( Plasmid profile) showed that 80 % of the Bacterial isolates contained plasmid of different molecular weights. | ||
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