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Some biochemical effects of lupinus albus L. seed oil on normal and alloxan induced diabetic mice | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 15, Issue 1, 2010, Pages 199-203 | ||
| Author | ||
| Fatima A.Mohammad | ||
| Abstract | ||
| In this research Lupin albus L. seed oil had been extracted and then identification of it is contents from the fatty acids and lipids which was compared with standard fatty acids and lipids by using thin layer chromotograph. Also the research has been dealed with the effects of increasing concentrations of (Lupin albus L.) seed oil on some biochemical parameters in serum and tissue of normal and alloxan-induced diabetic mice. When administrated orally (50,100,200) mg/Kg body weight of lupin seed oil the results indicated a significant decrease of serum glucose levels at 100 mg/kg body weight in normal and alloxan-induced diabetic mice the percentage of decrement was (-25.51% and -29.85%) respectively and then determined copper concentration in lupin oil by using atomic absorption spectrophotometer. Also noticed that the level of cholesterol in serum of normal and alloxan induced diabetic mice was significantly lowerd, the percentage of decreasing was (-22.39 and -23.09%) respectively. This research refer to significant decrease in liver glycogen content in normal mice of (-23.29%) after 180 min of administration of oil relative to control value. On the other hand, lupin seed oil has non significant difference on the concentration of liver glutathione and heart malondialdehyde relative to control value. | ||
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