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Discovery of An Antimicrobial Activity of Melia azedarach L. Extracts on Some Kinds of the Germs Isolated From Burns and Infectious Wounds . | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 15, Issue 3, 2010, Pages 154-161 | ||
| Author | ||
| Bassam Hussein Auoyb Al-Jumeily | ||
| Abstract | ||
| Melia azedarach L. is below to the family Meliaceae and used as medicinal plants which have been widely used in traditional folk medicine . Seeds oil have an antibacterial activity .So as different extracts have an antibacterial , antifungal , and antiviral activity . So that the present study aimed to detect and evaluate the antibacterial activity of bark and seeds extracts of Chinaberry . The study contained three species of bacteria which were Staphylococcus aureus , Staphylococcus epidermidis (Gram positive) and Pseudomonas aeruginosa (Gram negative) , all were isolated from burns and infectious wounds . Results show that ethyl acetate extract of bark of stem was having an inhibitory effect in all kinds of germs so, highest inhibition was in Staph. epidermidis , which appeared high sensitivity for different extract by comparintly with two species of bacteria . So the inhibition zone was (31) mm with the highest concentration (200)mg / ml , followed by methanolic extract of bark which showed an inhibitory effect higher than from seeds extracts , while for seed extracts , chloroformic extract have showed an highest effect among seed extracts . Followed by ethyl acetate extract while the methanolic extract of seeds have showed littlest effect among studied extracts . Also minimum inhibitory concentration and minimum bactericidal concentration have been determined which differs according to difference of extracts and its concentrations and processed germs up it . Also the present study have showed that G+ bacteria have appeared to be more sensitive than for Chinaberry extracts comparing with G- . | ||
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