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Synthesis and Biological study of N-Cysteine Derivatives Via a Schiff Base | ||
| Iraqi National Journal Of Chemistry | ||
| Article 1, Volume 0, Issue 30, 2014, Pages 297-305 | ||
| Author | ||
| Kasim Mohammed Hello | ||
| Abstract | ||
| Abstract This work includes the synthesis of some derivatives of cysteine and the biological activity was investigated. The aromatic Schiff base which prepared from aniline and benzaldehyde was reacted with α-chloroacetic acid and with different acid halide in dry benzene to give benzyl chloride (Compounds : 2, 3, 4, 6) which were reacted with L&D-Cysteine to give N-α-N¯-cystylbenzyl-N-alkanilide. The last synthesized compounds were identified by melting points, UV-Visible, IR and 1H-NMR spectrum. Thy were also tested against E.coli, Staphyllococus aureus, Klebsilla spp., Streptococcus pyogen, Listeria Moncytogen, Sallmonela typhi., Pseudoms aerugenosa and Brucella. | ||
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