Relationship between Anemia and Diastolic Dysfunction of the Heart

Abd Abdul Hussein, Mohammed

	Relationship between Anemia and Diastolic Dysfunction of the Heart
Medical Journal of Babylon
Article 1, Volume 9, Issue 1, 2012, Pages 166-181
Author
Mohammed Abd Abdul Hussein
Abstract
Background: Diastolic dysfunction is an echocardiographic pattern identified via transthoracic echocardiography. It is classified as primary or isolated when the systolic function is normal and secondary when there is systolic dysfunction. Aim of the study: This study is conducted to evaluate the relationship between anemia and diastolic dysfunction of the heart. Patients and methods: 200 participants were enrolled in this study and classified into two groups; anemic and non-anemic (n=100 for each) according to the definition of WHO. Measurements were taken for blood pressure, heart rate, and BMI. Standard biochemical indices, ECG and transthoracic Doppler echocardiography examination were also performed. Results: Of the anemic group, 8 participants had diastolic dysfunction and 92 patients did not. None of the control group had diastolic dysfunction. The difference was statistically significant. Among the anemic group, 12 participants had left ventricular hypertrophy while no subject from the control group had left ventricular hypertrophy. The correlation was statistically highly significant. Among these participants who had diastolic dysfunction, 6 participants had left ventricular hypertrophy and 2 participants had not. The correlation between left ventricular hypertrophy due to anemia and diastolic dysfunction was statistically highly significant. The severity of anemia was not correlating with the development and severity of diastolic dysfunction. Sex had no significant influence on the development of diastolic dysfunction in anemic participants. Conclusion: Anemia was identified to correlate well with the development of left ventricular hypertrophy and with the resultant diastolic dysfunction. The severity of diastolic dysfunction was unrelated to the severity of anemia and sex of the patients.

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