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BIOLOGICAL ACTIVITY OF SOME MIXED LIGAND COMPLEXES – PART II | ||
| AL-TAQANI | ||
| Article 1, Volume 22, Issue 4, 2009, Pages 130-137 | ||
| Authors | ||
| Zuhoor Fathi Dawood; Khider Daoud Sulyman; Muthana Jasim Muhammad | ||
| Abstract | ||
| The biological activity of some zinc (II) complexes containing mixed ligands having the formulaes [Zn(BBSCH)(LH)X] and [Zn(BBSC)(L)] (where BBSCH = benzilbis- (semicarbazone), BBSC- = deprotonated BBSCH ligand, LH = the ligands benzoinsemi- carbazone-BSH or 2-chlorobenzaldehydesemicarbazone-CSH or 2-fluorobenzaldehyde- semicarbazone-FSH or furaldehydesemicarbazone-FrSH, L = deprotonated LH ligand, X = SO42- or CO32-) in dimethylsulphoxide solution have been evaluated by agar plate diffution technique against five human pathogenic bacterial strains = Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Proteus mirabilis. The complexes were found to have antibacterial activity on some bacteria in vitro. The effective concentration of the complexes ranging between 1-10 µg/ml. Bacillus subtilis and Proteus mirabilis were the most sensitive bacteria followed by Staphylococcus aureus | ||
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