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تقييم مستوى الحركيات الخلوية في بلازما النساء ذوات مقدمة الارتعاج | ||
| Baghdad Science Journal | ||
| Article 1, Volume 8, Issue 4, 2011, Pages 918-925 | ||
| Authors | ||
| Abbass M.Rahmah; Amna N.Jassim; Suaad A. Brakhas | ||
| Abstract | ||
| This study is to evaluate plasma levels of several cytokines in preeclamptic pregnancies compared to those of healthy pregnancies. Ninety pregnant women with preeclampsia (37 mild & 53 severe) and thirty healthy pregnant women were enrolled in the study. Blood samples were taken and plasma levels of IL-8, IL-10, and IFN-γ were measured by enzyme-linked immunosorbent assay (ELISA). Preeclamptic women and their severe cases but not mild cases had significantly (P<0.05) increased levels of plasma IL-8, and IFN-γ as compared with healthy pregnancies. By contrast, plasma levels of IL-10 was significantly (P<0.05) increased in healthy pregnant women as compared to all groups of preeclampsia. Preeclampsia is associated with an imbalance between pro-inflammatory cytokines (IL-8, IFN-γ) and anti-inflammatory cytokines (IL-10), and these support our suggestion of altered immune response in preeclampsia. | ||
| Keywords | ||
| Preeclampsia; Immune response; cytokines | ||
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