- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
EFFECT OF PARACETAMOL ON SALIVA α-AMYLASE | ||
| karbala journal of pharmaceutical sciences | ||
| Article 22, Volume 2, Issue 2, 2011, Pages 257-263 PDF (0 K) | ||
| Author | ||
| Othman R. Hameed Alsamarrai | ||
| Abstract | ||
| The effect of paracetamol on the activity of saliva α-amylase was carried out. We prepared three different concentrations solutions of paracetamol (300, 500, 750) mg/100ml. The effect of different volumes (5, 10, 20, 30, 50) µl of paracetamol for each concentration were study. The results showed that paracetamol has inhibition effect on the activity of α-amylase enzyme and highest inhibition at 10µl of inhibitor, while the degree of inhibition for three different concentrations were (52.30, 54.34, 20.70) % respectively. Also, kinetic of enzyme showed km value 1.428 mmol/L, and Vmax value 30303.03 mol.liter-1.min-1, the result showed that inhibition is uncompetitive type. | ||
| Keywords | ||
| paracetamol; amylase | ||
|
Statistics Article View: 225 PDF Download: 148 |
||