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Metformin : The Treatment of Choise in Polycystic Ovary Disease | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 6, Issue 3, 2009, Pages 551-558 | ||
| Author | ||
| Melal Mohammed Abd. Al - Rudha | ||
| Abstract | ||
| Aim of study:Was to determine wheather metformin , which reduces hyperinsulinemia , would reverse the endocrinopathy of PCOS, allowing resumption of regular , normal menses. Subjects and Methods:A study included 29 patients with PCOS were treated with metformin for 3-6 months and effects on regulation of menstrual cycles, weight reduction, improvement in endocrinopathy was assessed after treatment. Results: Of 29 patients with PCOS,with menstual irregulation, the analysis showed that 20 patients resume normal menses after metformin therapy, 14 patients loss weight , and there was reduction in level of blood insulin and testosterone after treatment . Conclusion: Safe and effective therapy with metformin in PCOS reverses endocrinopathy , restores normal menstrual cycles , and restores fertility, allowing pregnancy. | ||
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