Prevalence of Diabetes and Hypocalcemia among Thalassemic  Patients in Thalassemia Center in Babylon Governorate

Shemran M. Al-Wtaify, Ahmed; Saihood H. Al-Shujairi, Ghafil

	Prevalence of Diabetes and Hypocalcemia among Thalassemic Patients in Thalassemia Center in Babylon Governorate
Medical Journal of Babylon
Article 1, Volume 6, Issue 3, 2009, Pages 672-679
Authors
Ahmed Shemran M. Al-Wtaify; Ghafil Saihood H. Al-Shujairi
Abstract
A prospective study was conducted on 129 patients with thalassemia, classified as 67 patients with β- thalassemia major, 52 patients β-thalassemia intermedia and 10 patients with sickle cell thalassemia, who were attending the thalassemia center at Babylon Maternity and Children teaching Hospital, from period of July 2008 to April 2009, their age ranged from 6 months – 26 years with mean age of 10.9 years. They were studied for diabetes and hypocalcemia. Four patients (3.1%) have diabetes and 28 patients (21.7%) have hypocalcemia with a mean level of serum calcium 1.61 ± 0.23 mmol/L in comparison to control group where they have 0 % diabetes and 10 patients (10%) hypocalcemia with mean level of serum calcium 1.9 ± 0.16 mmol/L. Risk factors for diabetes are age older than 15 years, frequent blood transfusion of more than 200 units and S. ferritin of more than 2000 µg/L. While, in hypocalcemia, the risk factors are age older than 5 years, blood transfusion of more than 50 unit and S. ferritin of more than 1000 µg/L. Also the study showed that diabetic patients associated with 100% short statures, 75% (hepatitis, heart failure, and delay sexual development) and 25% hypothyroidism. While in hypocalcemic patients associated with 75% short stature , 50% delay sexual development, 32.2% heart failure, 21.4%hepatitis, and 17.8% hypothyroidism .

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