Effect of Cadmium on Some Blood Components and Biochemical Parameters for Male Albino Mice Mus musculus

H. Jankeer, Muna

	Effect of Cadmium on Some Blood Components and Biochemical Parameters for Male Albino Mice Mus musculus
Tikrit Journal of Pure Science
Article 1, Volume 15, Issue 2, 2010, Pages 154-160
Author
Muna H. Jankeer
Abstract
The present study was designed included to investigate the effect of cadmium on some blood components and biochemical parameters in blood serum for male albino mice Mus musculus, Mice were divided into three groups (10mice/group). The first was giver a distilled water (as a drinking water) and used as a control, second group was given a drinking water containing the concentration of (50) mg cadmium/L and the third group was given a drinking water containing the concentration of (150) mg cadmium/L. All groups were treated daily for a period of (30) days. The results revealed a decrease in the haemoglobim concentration of blood, packed cell volume and total erythrocyte count in the blood of treated mice with those concentrations compared with control. The reduction in the above mentioned parameters was progressive with the time of treatment and it was more prominent in animals treated with (150) mg cadmium/L. The results also showed a significant in the total protein concentration in blood serum of mice treatment with those concentration compared with control group, Cadmium also caused a significant increase in total uric acid, cholesterol concentration and the enzyme activity of transaminases (Alanine aminotransferase "ALT" and Aspartate aminotransferase "AST") in blood serum as compared with control group and the results showed that reduction and highest were more prominent in mice treatment with (150) mg cadmium/L of drinking water.

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